May 21, 2026 · 6 min read

How to Evaluate a 510(k) Predicate Before Committing

A checklist for evaluating predicate candidates before you build a submission around them. Covers clearance fit, post-market history, enforcement record, and chain integrity.

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May 21, 2026 · 6 min read

FDA Warning Letters and 510(k) Predicate Research

A predicate applicant's FDA warning letter history can affect the strength of your 510(k) submission. Here's what warning letters reveal and how to factor them into predicate selection.

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May 21, 2026 · 6 min read

What FDA Enforcement History Tells You About a Predicate

FDA's view of a device type doesn't stop at clearance. Enforcement actions in the years after clearance reveal how regulators think about a device's risks in practice.

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May 10, 2026 · 6 min read

510(k) vs PMA: Which FDA Pathway Does Your Device Need?

Most medical device companies assume 510(k) is the default FDA pathway. It often is — but understanding when a PMA is required, and when De Novo makes more sense, can save you years.

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May 6, 2026 · 6 min read

FDA 510(k) Review Timeline: What to Expect and How to Prepare

FDA has a 90-day statutory review goal for 510(k)s. Most submissions take longer. Here's what actually drives the timeline — and what you control.

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April 28, 2026 · 7 min read

The De Novo Pathway: When to Use It and How It Works

De Novo isn't a fallback when you can't find a predicate — it's a strategic pathway for novel devices that creates regulatory precedent for an entire product category.

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April 18, 2026 · 7 min read

510(k) for Combination Products: Drug-Device, Biologic-Device, and More

Combination products occupy some of the most complex regulatory territory FDA administers. Understanding primary mode of action and lead center assignment is essential before you file.

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