May 21, 2026 · 6 min read

Why Adverse Event History Matters When Choosing a 510(k) Predicate

MAUDE adverse event reports can reveal post-market problems with a predicate device before you commit to it. Here's how to use FDA's adverse event database in your predicate research.

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May 21, 2026 · 6 min read

Understanding Predicate Chains in 510(k) Research

Every 510(k) predicate was itself cleared based on an earlier predicate. Tracing that lineage generation by generation can reveal risks your submission needs to address.

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May 15, 2026 · 7 min read

How to Find a Predicate Device for Your 510(k) Submission

Finding the right predicate is the most consequential decision in a 510(k) submission. Here's the systematic approach regulatory consultants actually use.

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May 12, 2026 · 7 min read

How to Write Section 4 of an FDA eSTAR: Predicate Device Comparison

Section 4 is where your substantial equivalence argument lives. It's the section FDA reviewers read most carefully — and the one most likely to generate Additional Information requests.

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April 22, 2026 · 5 min read

How to Search the FDA 510(k) Database Effectively

FDA's 510(k) database contains 175,000+ clearances going back to 1976. Here's how to search it strategically — not just successfully.

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